|
rs1004446
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed an inverse association with IGFII rs3741211 and endometrial cancer risk (OR=0.79 (95% CI: 0.63, 0.99)) and IGFII rs1004446 and endometrial cancer risk (OR=0.80 (95% CI: 0.68, 0.94)).
|
21078522 |
2011 |
|
rs3741211
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed an inverse association with IGFII rs3741211 and endometrial cancer risk (OR=0.79 (95% CI: 0.63, 0.99)) and IGFII rs1004446 and endometrial cancer risk (OR=0.80 (95% CI: 0.68, 0.94)).
|
21078522 |
2011 |
|
rs1063539
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed an epistatic interaction between survivin rs9904341 CC+CG genotype and ADIPOQ rs1063539 GG genotype increasing the risk of EC compared to those with other genotypes [OR: 4.86(1.88-12.54), P=0.001].
|
25613698 |
2015 |
|
rs9904341
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed an epistatic interaction between survivin rs9904341 CC+CG genotype and ADIPOQ rs1063539 GG genotype increasing the risk of EC compared to those with other genotypes [OR: 4.86(1.88-12.54), P=0.001].
|
25613698 |
2015 |
|
rs2066992
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed a significant increase in risk of endometrial cancer of rs1524107 (IL6) (T/C, OR = 1.61, 95% CI = 1.09-2.37, p = 1.55 × 10<sup>-2</sup> ), rs2066992 (IL 6) (OR = 3.09, 95% CI = 2.11-4.53, p = 3.13 × 10<sup>-9</sup> ).
|
30828987 |
2019 |
|
rs1524107
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed a significant increase in risk of endometrial cancer of rs1524107 (IL6) (T/C, OR = 1.61, 95% CI = 1.09-2.37, p = 1.55 × 10<sup>-2</sup> ), rs2066992 (IL 6) (OR = 3.09, 95% CI = 2.11-4.53, p = 3.13 × 10<sup>-9</sup> ).
|
30828987 |
2019 |
|
rs369410616
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed a significant association between endometrial cancer risk and XRCC1 rs1799782 (C > T, Arg194Trp) and XRCC1 rs25487 (G > A, Arg399Gln).
|
24172093 |
2013 |
|
rs25487
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed a significant association between endometrial cancer risk and XRCC1 rs1799782 (C > T, Arg194Trp) and XRCC1 rs25487 (G > A, Arg399Gln).
|
24172093 |
2013 |
|
rs746702110
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed a significant association between endometrial cancer risk and XRCC1 rs1799782 (C > T, Arg194Trp) and XRCC1 rs25487 (G > A, Arg399Gln).
|
24172093 |
2013 |
|
rs1799782
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We observed a significant association between endometrial cancer risk and XRCC1 rs1799782 (C > T, Arg194Trp) and XRCC1 rs25487 (G > A, Arg399Gln).
|
24172093 |
2013 |
|
rs700519
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed a multiplicative interaction between single nucleotide polymorphism rs700519 and body mass index among postmenopausal women (P = 0.01), with stronger associations between rs700519 genotypes and endometrial cancer risk among heavier (body mass index, >or=25) postmenopausal women.
|
17507620 |
2007 |
|
rs605059
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We identified and genotyped two haplotype-tagging SNPs (+1004C/T and +1322C/A), and genotyped an additional SNP [+1954A/G (Ser312Gly)] in nested case-control studies of endometrial cancer (cases = 222, controls = 666) and breast cancer (cases = 1007, controls = 1441) in the prospective Nurses' Health Study.
|
14973105 |
2004 |
|
rs4430796
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We identified an endometrial cancer susceptibility locus close to HNF1B at 17q12 (rs4430796, P = 7.1 × 10(-10)) that is also associated with risk of prostate cancer and is inversely associated with risk of type 2 diabetes.
|
21499250 |
2011 |
|
rs9838411
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We found the following: (1) PIK3CA rs6443624 and rs9838411 variants either borderline or significantly decreased risk of endometrial cancer in a dominant model (adjusted odds ratio [OR], 0.62; 95% CI, 0.39-1.00 and 0.59; 95% CI, 0.36-0.95, respectively).
|
22146979 |
2012 |
|
rs6259
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We found that the Asp(327)Asn (rs6259) polymorphism was associated with decreased risk of endometrial cancer, particularly among postmenopausal women (OR = 0.79, 95% CI = 0.62-1.00).
|
19005973 |
2008 |
|
rs1056836
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We found that CYP1B1 gene L432V polymorphism was associated with a significantly increased risk of endometrial cancer (G vs. C: OR=1.23, 95% CI: 1.06-1.43, P=0.007; GC+GG vs. CC:OR=1.24, 95% CI: 1.08-1.43, P=0.003; GC vs. CC: OR=1.16, 95% CI: 1.04-1.29, P=0.009).
|
21191305 |
2011 |
|
rs9340799
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We found an association between rs2234670, rs2234693, as well as rs9340799, markers in strong linkage disequilibrium (LD), and endometrial cancer risk.
|
18990228 |
2008 |
|
rs2234693
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We found an association between rs2234670, rs2234693, as well as rs9340799, markers in strong linkage disequilibrium (LD), and endometrial cancer risk.
|
18990228 |
2008 |
|
rs112843513
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We examined the association between five single nucleotide polymorphisms (rs185903567, rs116645643, rs115160714, rs116195487, and rs112843513) located in the 3'UTR region of the TopBP1 gene and endometrial cancer risk as well as allele-specific gene expression.
|
24346708 |
2014 |
|
rs4680
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We evaluated the association between the CYP1B1 Leu432Val and CYP1B1 Asn453Ser polymorphisms and the COMT Val158Met polymorphism and invasive endometrial cancer risk in a case-control study nested within the Nurses' Health Study (n = 222 cases, 666 controls).
|
14656940 |
2004 |
|
rs1800440
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We evaluated the association between the CYP1B1 Leu432Val and CYP1B1 Asn453Ser polymorphisms and the COMT Val158Met polymorphism and invasive endometrial cancer risk in a case-control study nested within the Nurses' Health Study (n = 222 cases, 666 controls).
|
14656940 |
2004 |
|
rs1056836
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We evaluated the association between the CYP1B1 Leu432Val and CYP1B1 Asn453Ser polymorphisms and the COMT Val158Met polymorphism and invasive endometrial cancer risk in a case-control study nested within the Nurses' Health Study (n = 222 cases, 666 controls).
|
14656940 |
2004 |
|
rs2676530
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We did not find that the rs2676530 polymorphism was significantly associated with endometrial cancer risk.
|
17301695 |
2007 |
|
rs1048943
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We did not observe any statistically significant associations between the MspI, Thr461Asn or Ile462Val polymorphisms and endometrial cancer risk or any significant effect modification by cigarette-smoking status.
|
17717632 |
2007 |
|
rs1799814
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We did not observe any statistically significant associations between the MspI, Thr461Asn or Ile462Val polymorphisms and endometrial cancer risk or any significant effect modification by cigarette-smoking status.
|
17717632 |
2007 |